Download Cancer and Aging: From Bench to Clinics by M. Extermann, T. Fulop PDF

By M. Extermann, T. Fulop

Melanoma is obviously an age-related ailment. fresh learn in either getting older and melanoma has proven the advanced interplay among the 2 phenomena. This impacts a large spectrum of study and perform, wherever from simple examine to healthiness care association. middle examples of those shut institutions are addressed during this e-book. beginning with uncomplicated examine, the 1st chapters conceal melanoma improvement, mTOR inhibition, senescent cells changing the tumor microenvironment, and immune senescence affecting melanoma vaccine reaction. taking into consideration the multidisciplinarity of geriatric oncology, a number of chapters concentrate on geriatric and oncologic points in sufferer evaluation, remedies, nursing and workout courses. The publication is rounded off by way of a dialogue at the influence of the metabolic syndrome illustrating the interactions among comorbidity and melanoma and a bankruptcy on frailty. This publication offers the reader with insights that would expectantly foster his or her mirrored image of their personal learn and perform to additional the improvement of this most fun box. Given the getting older of the inhabitants all over the world and the excessive occurrence of melanoma, it's crucial studying not just for oncologists and geriatricians yet for all overall healthiness practitioners.

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J Leukoc Biol 2004; 76:291–199. 14 Biron CA, Brossay L: NK cells and NKT cells in innate defense against viral infections. Curr Opin Immunol 2001;13:458–464. 15 Re F, Donnini A, Bartozzi B, et al: Circulating γδT cells in young/adult and old patients with cutaneous primary melanoma. Immun Ageing 2005;2:2. 16 Argentati K, Re F, Donnini A, et al: Numerical and functional alterations of circulating γδT lymphocytes in aged people and centenarians. J Leukoc Biol 2002;72:65–71. 17 Sauerwein-Teissl M, Schonitzer D, GrubeckLoebenstin B: Dendritic cell responsiveness to stimulation with influenza vaccine is unimpaired in old age.

31 Kuilman T, et al: Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008;133:1019–1031. 32 Krizhanovsky V, et al: Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology. Cold Spring Harb Symp Quant Biol 2008;73:513–522. 33 Krizhanovsky V, et al: Senescence of activated stellate cells limits liver fibrosis. Cell 2008;134:657–667. 34 Xue W, et al: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.

39 Liotta LA, Kohn EC: The microenvironment of the tumour-host interface. Nature 2001;411:375–379. 40 Bavik C, et al: The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res 2006;66:794–802. 41 Parrinello S, et al: Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci 2005;118: 485–496. 42 Laberge RM, et al: Epithelial-mesenchymal transition induced by senescent fibroblasts.

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