Download Coenzyme Q: Molecular mechanisms in health and disease by Kagan V., Quinn P. (eds.) PDF

By Kagan V., Quinn P. (eds.)

Given that its discovery in 1957, Coenzyme Q has piqued the curiosity of scientists from quite a lot of disciplines due to its bioenergetics, vitamin-like habit, and interactions with antioxidant supplementations E and C. Coenzyme Q: Molecular Mechanisms in wellbeing and fitness and sickness is a finished treatise in this often-studied coenzyme. overseas specialists hide the learn that resulted in its emergence as an exhilarating, new nutritional supplement.The current quantity summarizes the most recent advancements in a number of parts of CoQ learn. New options on extramitochondrial features of CoQ are mentioned in chapters, whereas fresh discoveries in biosynthetic pathways for CoQ according to molecular genetic ways are provided in one other chapter.Further chapters discover the function of CoQ as an antioxidant, revealing the necessity for added study during this fascinating region. This ebook can be of utmost curiosity to biochemists, biophysicists, molecular and phone biologists, in addition to nutritionists and biomedical medical experts.

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111. Stoner, C. , Steady-State Kinetics of the Overall Oxidative Phosphorylation Reaction in Heart Mitochondria. Determination of the Coupling Relationships Between the Respiratory Reactions and Miscellaneous Observations Concerning Rate-Limiting Steps, Bioenerg. , 16, 115, 1984. 112. , Coenzyme Q homologs and vitamin E in synaptic and non-synaptic occipital cerebral cortex mitochondria in the aging rat, Mol. ), S279, 1997. 2 Topography of Coenzyme Q in Membranes Peter J. 1 INTRODUCTION Coenzyme Q is a fat-soluble component of electron transport chains and, in consequence, it tends to partition into lipophilic organelles of the body such as membranes, lipoproteins, and fat.

Natl. Acad. , USA, 81, 2606, 1984. 52. Hughes, B. , Pailthorpe, B. , White, L. , and Sawyer, W. , Extraction of membrane microviscosity from translational and rotational diffusion coefficients, Biophys. , 37, 673, 1982. 53. , On coenzyme Q orientation in membranes: a linear dichroism study of ubiquinones in a model bilayer, J. Membr. , 128, 193, 1992. 54. , Localization and preferred orientations of ubiquinone homologs in model bilayers, Biochem. Cell. , 70, 504, 1992. 55. , Vectorial redox reactions of physiological quinones.

REFERENCES 1. Crane, F. , Isolation of a quinone from beef heart mitochondria, Biochim. Biophys. Acta, 1000, 358, 1989. 2. Crane, F. L. , The diversity of coenzyme Q function, Molec. , 8, s1–s6, 1997. 3. Beyer, R. , The role of ascorbate in antioxidant protection in biomembranes. Interaction with vitamin E and Coenzyme Q, J. Bioenerg. , 26, 349, 1994. 4. Ernster, L. , Biochemical, physiological and medical aspects of ubiquinone function, Biochim. Biophys. Acta, 1271, 195, 1995. 5. Maguire, J. , Ackrell, B.

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