By John W. Miller, Daniel L. Silbergeld
Supplying authoritative assurance of the tremendous array of significant medical concerns in epilepsy surgery-from the choice of surgical applicants to presurgical assessment, surgical concepts, and postoperative rehabilitation-this reference offers a chain of essays at the rules and controversies within the box with targeted segments that specific opposing viewpoints through skilled clinicians within the self-discipline.
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Extra info for Epilepsy Surgery: Principles and Controversies (Neurological Disease and Therapy)
57. Semah F, Picot MC, Adam C, Broglin D, Arzimanoglou A, Bazin B, Cavalcanti D, Baulac M. Is the underlying cause of epilepsy a major prognostic factor for recurrence?. Neurology 1998; 51:1256–1262. 58. Stephen LJ, Kwan P, Brodie MJ. Does the cause of localisation-related epilepsy inﬂuence the response to antiepileptic drug treatment? Epilepsia 2001; 42:357–362. 59. Regesta G, Tanganelli P. Clinical aspects and biological bases of drug-resistant epilepsies. Epilepsy Res 1999; 34:109–122. 60. Bocti C, Robitaille Y, Diadori P, Lortie A, Mercier C, Bouthillier A, Carmant L.
What is the number of AEDs that the patient has to fail before the chance of subsequent success is sufﬁciently low to designate the seizure disorder as pharmacoresistant? No drug can be effective in all patients and so those who have not responded to one AED may beneﬁt from an alternative (91,92). In the Glasgow series, 50% of the patients entered a remission period of 12 months or more with their ﬁrst ever AED, whereas those who received a second and third monotherapy only entered remission in 32% and 27% of the cases, respectively.
Neurology 1999; 52:132–136. 44. Kalviainen R, Salmenpera T. Do recurrent seizures cause neuronal damage? A series of studies with MRI volumetry in adults with partial epilepsy. Prog Brain Res 2002; 135:279–295. 45. Briellmann RS, Berkovic SF, Syngeniotis A, King MA, Jackson GD. Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. Ann Neurol 2002; 51:641–644. 46. Fuerst D, Shah J, Shah A, Watson C. Hippocampal sclerosis is a progressive disorder: a longitudinal volumetric MRI study.