Download Pulmonary Biology in Health and Disease by Nai-San Wang (auth.), E. Edward Bittar MD (eds.) PDF

By Nai-San Wang (auth.), E. Edward Bittar MD (eds.)

Pulmonary Biology in health and wellbeing and ailment was once conceived as a better half to a handful of pricy, multivolume textbooks. this can be a part of the promising development to post shorter textbooks at the matters of lung biology and transforming. Whoever understands human biology and the far-reaching results of the genome and postgenome revolutions is apt to concede that the center-piece in home improvement lies within the ?eld of m- ecular cardiobiology. The ?eld of molecular cardiobiology comprises the syndrome of persistent middle failure in addition to ischemic cardioprotection. through analogy, the center-piece in pulmonobiology is continual bronchial asthma. Key issues within the current quantity contain s- naling mechanisms regulating the endothelium and delicate muscle cells,in?ammatory cells, mediators, airway floor liquid, and pharmacological remedy that specializes in how in?amed airlines are altered. Written essentially for predoctoral and postdoctoral graduates within the easy clinical sciences, the clinical scholar and postdoctoral doctor, graduates within the allied s- ences, nurses, pulmonologists, and physicians in serious care medication, this booklet p- vides a number of the basics of up to date pulmonology. it truly is divided into numerous components dedicated to the regulate of breathing, arterial chemoreceptors,muscles of air flow, pulmonary body structure, and gasoline alternate in future health, workout, and sickness. exact emphasis is put on emphysema and its pathobiology, acute lung harm, bronchial asthma and inhaled toxicants. as the ?eld is usually evolving, each one bankruptcy contains urged readings that lead the reader to assets of extra info, reminiscent of the assessment on home improvement of the blood gasoline barrier through West and Mathieu-Costello.

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Extra resources for Pulmonary Biology in Health and Disease

Sample text

Exp. Lung Res. 4, 137–156. St.

Cytochem. 37, 869–875. J. (1986) Differentiation of tracheal epithelium during fetal lung maturation in the rhesus monkey macaca mulata. Am. J. Anat. 175, 59–71. R. (1997) Clara cells. J. ) pp. 517–534. Lippincott-Raven, Philadelphia. M. (1979) Composition and control of secretions from tracheal bronchial submucosal glands. Nature 279, 551–552. Reid, L. (1960) Measurement of the bronchial mucous gland layer: a diagnostic yardstick in chronic bronchitis. Thorax 15, 132–141. , et al. (1989) Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Basal cells are small, roughly spherical cells that are approximately 7 mm diameter and lie on the basement membrane between the ciliated and secretory cells (see Fig. 1A). They may comprise up to 50% of the cells in the tracheal and bronchial epithelia of the large mammalian species. Their cytoplasm is distinguished by bundles of tonofilaments, and they are connected to neighboring columnar cells by numerous desmosomes. They contain hemidesmosomes where they abut on the basement membrane. H. , 1979).

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