By Babak Kateb, John D. Heiss
Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the aptitude to revolutionize drugs and enhance the prevention, prognosis, and remedy of neurological problems over the following 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery offers a state of the art assessment of the sphere, supplying present information regarding nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology.
The textual content additionally studies the most recent regulatory guidance that impression the interpretation of nanotechnological learn from the laboratory to the medical institution, in addition to the latest info on biodevices and pharmaceutical spinoffs. It highlights presidential and congressional tasks and courses which may considerably impression the sector within the close to destiny. Chapters talk about the most recent technology and technologies—which are utilized to prognosis and remedy of neurological disorders—as good as regulatory matters that impression product development.
This quantity describes advances that experience already been translated to the hospital or carry major promise for destiny program in nanoneurosurgery, in addition to their power effect. A full-color textual content, the e-book includes contributions by means of greater than one hundred twenty researchers, unique and descriptive illustrations, and greater than 3,000 references. supplying extensive insurance of nanotechnological purposes in varied components and addressing FDA rules and healthcare coverage, this quantity presents a starting place of principles and strategies for scientists and physicians to plot winning, much less invasive tactics for destiny therapy of fearful procedure disorders.
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Extra resources for The Textbook of Nanoneuroscience and Nanoneurosurgery
In delivering substances like fluorescent markers, proteins, genes, and chemical substances to regions of inflammation or tumor in a mouse model, the accumulation of liposomes with SLX was much higher than in controls. In conjunction with local hyperthermia, LTSLs containing chemotherapy drugs were found to increase tumor drug concentrations and improve antitumor efficacy of the drugs. 3 Nanoscale Platforms Presently Being Developed for Use in Nanomedicine Winter et al. 2006 Ponce et al. 2007 (continued) Hirai et al.
1 Nanotechnology Timeline 19th century 1905 1931 1936 1947 1940s 1950 1951 1956 1958 1959 1965 1974 1976 1979 1981 1985 Ceramic filters used to separate viruses from cells (nanoscale porosity). Estimation of sugar molecule diameter (1 nm) by Einstein. Discovery of electron microscope by Max Knoll and Ernst Ruska. gov 2011). gov 2011). Patch clamp technique uses nanoscale capillary probes to examine individual cell surface receptors (Tibbals 2011). Electron microscope and x-ray crystallography enabled observation of nanoscale structures (Tibbals 2011).
First nanotechnology company, Zybex, established. The Interagency Working Group on Nanotechnology (IWGN) was formed under the National Science and Technology Council to investigate the state of the art in nanoscale science and technology and to forecast possible future developments. gov 2011). Bruchez et al. demonstrated the first use of nanocrystals as biological labels. Trung-Lee et al. used DNA-gelatin nanospheres for controlled gene delivery. Freitas used the term “nanomedicine” in a publication.